Dr. Petkovich is a
co-founder of Cytochroma and has provided scientific
guidance as a consultant until 2006 when he joined the
Company as a full-time Chief Scientific Officer (CSO).
Dr. Petkovich served as a Director of the Company until
his appointment as CSO. Dr. Petkovich has been involved
in all of the Company’s
efforts to raise capital and played a pivotal role in
completing Cytochroma’s first license agreement
(with Allergan, Inc.) and served as Chair of the Joint
Research Management Committee established under this
agreement. Dr. Petkovich received his B.Sc. from McMaster
University in 1981 and Ph.D. in Biochemistry in 1986
from the University of Toronto. He was a post-doctoral
fellow in the laboratory of Dr. Pierre Chambon in Strasbourg,
France from 1986 to 1989. He moved to Queen's University
in 1990 to join the Departments of Biochemistry and Pathology
and was appointed Full Professor in 1998. Dr. Petkovich
is an expert in small molecule signaling, nuclear receptors
and metabolism and much of his work since 1981 has focused
on vitamins D and A. Dr. Petkovich discovered the fundamental
mechanism of action of vitamin A by cloning the first
receptor for the vitamin A metabolite, retinoic acid
and further went on to characterize a family cytochrome
P450 enzymes critical for modulating retinoic activity.
These discoveries are cited as major breakthroughs in
the vitamin A field.